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Rocuronium

羅庫諾林

Mechanism of action:

Rocuronium 是一種非去極化型胺基類固醇神經肌肉阻斷劑（non-depolarizing aminosteroid neuromuscular blocker）。Rocuronium 會與運動終板（motor end-plate）上的菸鹼型乙醯膽鹼受體（nicotinic acetylcholine receptor）抑制性結合，阻止乙醯膽鹼（acetylcholine）引發去極化（depolarization），造成可逆性的骨骼肌鬆弛與麻痺。

​Reference(s):

1. Agoston S et al. (1992). Clinical pharmacokinetics of neuromuscular blocking drugs. Clin Pharmacokinet. 


2. Khuenl-Brady KS et al. (1996). Clinical pharmacokinetics of rocuronium bromide. Clin Pharmacokinet. 


3. Alvarez-Gomez JA et al. (1997). [Rocuronium]. Rev Esp Anestesiol Reanim.

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