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The Sound of Evolution
Roxithromycin
羅紅黴素
Mechanism of action:
Roxithromycin 是一種巨環內酯類抗生素（macrolide antibiotic），作用於細菌的 50S 核糖體亞基，與 23S rRNA 鄰近肽鏈出口通道的區域結合，阻止轉位（translocation）與肽鏈延長，使細菌的蛋白質合成無法進行，導致細菌生長停滯。
Reference(s):
Gentry LO et al. (1987). Roxithromycin, a new macrolide antibiotic, in the treatment of infections in the lower respiratory tract: an overview. J Antimicrob Chemother.
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