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Stanozolol

司坦唑醇

Mechanism of action:

Stanozolol 屬於一種 17α-烷基化合成代謝類固醇（17α-alkylated anabolic steroid）。Stanozolol 進入細胞後，與細胞質中的雄激素受體（androgen receptor）結合，形成複合體，並轉位進入細胞核，與 DNA 上的雄激素反應元件（androgen response element）結合，提升蛋白質合成、氮保留、細胞生長相關的基因表達。

​Reference(s):

1. Guilarte M et al. (2008). Acquired angioedema associated with hereditary angioedema due to C1 inhibitor deficiency. J Investig Allergol Clin Immunol. 


2. Thevis M et al. (2010). Synthetic anabolic agents: steroids and nonsteroidal selective androgen receptor modulators. Handb Exp Pharmacol. 


3. Sloane DE et al. (2007). Hereditary angioedema: Safety of long-term stanozolol therapy. J Allergy Clin Immunol.

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