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Tetracycline

四環黴素

Mechanism of action:

Tetracycline 是一種四環黴素類抗生素(tetracycline antibiotic)。Tetracycline 能可逆性結合於細菌核糖體的 30S 亞基,阻止氨醯-tRNA(aminoacyl-tRNA)與 mRNA-核糖體複合體結合,使新的胺基酸無法加入肽鏈,導致蛋白質無法生成。

​Reference(s):

1. Griffin MO et al. (2010). Tetracyclines: a pleitropic family of compounds with promising therapeutic properties. Review of the literature. Am J Physiol Cell Physiol. 


2. U.S. FDA. (n.d.). Code of Federal Regulations 216.24: Drug products withdrawn or removed from the market for reasons of safety or effectiveness.

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