Peto's Paradox: Why Are Larger, Longer-Lived Animals Less Likely to Develop Cancer?
- 演化之聲
- Mar 15
- 5 min read
Updated: Apr 10
Cancer cells arise when normal cells accumulate errors in DNA replication across many generations of cell division. As these mutations continue to accumulate, the DNA of descendant cells gradually diverges from that of the original healthy cell lineage. This divergence disrupts normal cellular function and leads to abnormal physiological behavior. Within the body, such cells become harmful. If they continue to proliferate, they may initially disrupt the function of a local tissue, and in more severe cases they may metastasize throughout the body, ultimately impairing vital physiological functions and leading to the death of the organism.
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